intracellular glutathione Schematic of (GSH)-triggered release of GCEL Intracellular Glutathione Capsules |

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The sacrifice was at day 3, 5, 7, and 14

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ENT-01 ( squalamine phosphate ) inhibits -synuclein aggregation in the gastrointestinal tract and significantly increased the number of complete spontaneous bowel movements per week after 25 days on ENT-01 treatment in a double-blind, placebo-controlled, phase 2b RCT in 150 participants with PD and constipation however at the expense of gastrointestinal AEs in up to one third of participants [166]